Mutation Mass Shifts
This table lists the delta masses between various amino acids and can be used to help explain how an observed mass change could represent an AA mutation.
- Residues DOWN the left indicate the EXPECTED residues.
- Residues ACROSS the top indicate the MUTANT residues.
| G | A | S | P | V | T | C | L/I | N | D | Q/K | E | M | H | F | R | Y | W | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 57 | 71 | 87 | 97 | 99 | 101 | 103 | 113 | 114 | 115 | 128 | 129 | 131 | 137 | 147 | 156 | 163 | 186 | |||
| ________________________________________________________________________ | ||||||||||||||||||||
| G | 57 | 14 | 30 | 40 | 42 | 44 | 46 | 56 | 57 | 58 | 71 | 72 | 74 | 80 | 90 | 99 | 106 | 129 | ||
| A | 71 | -14 | 16 | 26 | 28 | 30 | 32 | 42 | 43 | 44 | 57 | 58 | 60 | 66 | 76 | 85 | 92 | 115 | ||
| S | 87 | -30 | -16 | 10 | 12 | 14 | 16 | 26 | 27 | 28 | 41 | 42 | 44 | 50 | 60 | 69 | 76 | 99 | ||
| P | 97 | -40 | -26 | -10 | 2 | 4 | 6 | 16 | 17 | 18 | 31 | 32 | 34 | 40 | 50 | 59 | 66 | 89 | ||
| V | 99 | -42 | -28 | -12 | -2 | 2 | 4 | 14 | 15 | 16 | 29 | 30 | 32 | 38 | 48 | 57 | 64 | 87 | ||
| T | 101 | -44 | -30 | -14 | -4 | -2 | 2 | 12 | 13 | 14 | 27 | 28 | 30 | 36 | 46 | 55 | 62 | 85 | ||
| C | 103 | -46 | -32 | -16 | -6 | -4 | -2 | 10 | 11 | 12 | 25 | 26 | 28 | 34 | 44 | 53 | 60 | 83 | ||
| L/I | 113 | -56 | -42 | -26 | -16 | -14 | -12 | -10 | 1 | 2 | 15 | 16 | 18 | 24 | 34 | 43 | 50 | 73 | ||
| N | 114 | -57 | -43 | -27 | -17 | -15 | -13 | -11 | -1 | 1 | 14 | 15 | 17 | 23 | 33 | 42 | 49 | 72 | ||
| D | 115 | -58 | -44 | -28 | -18 | -16 | -14 | -12 | -2 | -1 | 13 | 14 | 16 | 22 | 32 | 41 | 48 | 71 | ||
| Q/K | 128 | -71 | -57 | -41 | -31 | -29 | -27 | -25 | -15 | -14 | -13 | 1 | 3 | 9 | 19 | 28 | 35 | 58 | ||
| E | 129 | -72 | -58 | -42 | -32 | -30 | -28 | -26 | -16 | -15 | -14 | -1 | 2 | 8 | 18 | 27 | 34 | 57 | ||
| M | 131 | -74 | -60 | -44 | -34 | -32 | -30 | -28 | -18 | -17 | -16 | -3 | -2 | 6 | 16 | 25 | 32 | 55 | ||
| H | 137 | -80 | -66 | -50 | -40 | -38 | -36 | -34 | -24 | -23 | -22 | -9 | -8 | -6 | 10 | 19 | 26 | 49 | ||
| F | 147 | -90 | -76 | -60 | -50 | -48 | -46 | -44 | -34 | -33 | -32 | -19 | -18 | -16 | -10 | 9 | 16 | 39 | ||
| R | 156 | -99 | -85 | -69 | -59 | -57 | -55 | -53 | -43 | -42 | -41 | -28 | -27 | -25 | -19 | -9 | 7 | 30 | ||
| Y | 163 | -106 | -92 | -76 | -66 | -64 | -62 | -60 | -50 | -49 | -48 | -35 | -34 | -32 | -26 | -16 | -7 | 23 | ||
| W | 186 | -129 | -115 | -99 | -89 | -87 | -85 | -83 | -73 | -72 | -71 | -58 | -57 | -55 | -49 | -39 | -30 | -23 | ||
All values are (column-row). The mass difference observed is consistent with a ROW to COLUMN mutation.
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